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MS is an autoimmune disease that assaults myelin, the insulating cowl of cells within the mind and spinal cord. Stem cell therapy is an experimental procedure being studied in MS to "reset" the immune system so that it is much less more likely to assault myelin. Since the first human research in 1995, stem cell therapy has proven great potential for stopping MS illness exercise, but with dangers of serious complications. Ongoing studies are attempting to find out which individuals with MS will profit most from stem cell therapy, and which stem cell therapy methods are safest and best.

Studies of stem cell therapy for MS typically use a kind of stem cell therapy referred to as autologous hematopoetic stem cell therapy (aHSCT). Autologous means the stem cells used for therapy are taken from the treated person’s personal physique. Hematopoetic stem cells (HSC) are grownup stem cells found in bone marrow and blood, https://stemcellscosts.com/ and are capable of producing all the cells that make up the blood and immune system. The technique of aHSCT starts with medications that launch stem cells from the bone marrow into the blood. These stem cells are then collected and frozen. This is adopted by a remedy course of excessive-dose chemotherapy to eradicate the remaining immune system. Finally, the beforehand collected stem cells are infused back into the person’s blood and stimulated to repopulate the person’s immune system "from scratch."

This one-time course of normally takes place in the hospital over several weeks. You possibly can read more particulars of the process at this National MS Society webpage including what happens through the remedy, after remedy, risks and advantages of stem cell therapy, finding stem cell remedies, and assets to study extra.

Still being investigated is how and when to make use of aHSCT to deal with MS and the security of aHSCT in comparison with other MS therapies. The BEAT-MS examine, presently ongoing at a number of websites across the United States, will assist reply this query in folks with aggressive MS who aren't responding optimally to accessible MS medications. Currently, aHSCT stays experimental for MS and the VA doesn't offer stem cell therapy for individuals with MS. The VA MS Centers of Excellence strongly urge Veterans with MS to keep away from getting aHSCT from for-revenue and unaccredited stem cell centers. We encourage those excited about contemplating aHSCT to debate it further with their physician and seek the advice of the resources beneath.

Additional Information

National MS Society: Stem Cells in MS

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